产品货号：
Z36752
中文名称：
IkB Alpha/NFKBIA抗体
英文名称：
Anti-IkB Alpha/NFKBIA Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IkB Alpha/NFKBIA Antibody |
| 指标别名 | I kappa B alpha;IkappaBalpha;IkB alpha;IKBA;Ikβ-α;MAD 3;MAD3;NF kappa B inhibitor alpha;NFKBI;NFKBIA |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | NFKBIA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human IKB alpha |
| 实际分子量 | 39KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | NFKBIA,also called IKBA or MAD-3,is one member of a family of cellular proteins that function to inhibit the NF-κB transcription factor.It is mapped to 14q13.2.NFKBIA inhibits NF-κB by masking the nuclear localization signals(NLS) of NF-κB proteins and keeping them sequestered in an inactive state in the cytoplasm.It moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export.The effect of the nonpathogenic bacteria is specific to the SCF complex substrates CTNNB1 and NFKBIA.This may help to explain the beneficial effects of treatment of inflammatory bowel disease with nonpathogenic probiotic enteric organisms.In addition,NFKBIA blocks the ability of NF-κB transcription factors to bind to DNA,which is required for NF-κB's proper functioning. |
| Uniprot ID | P25963 |
| 基因名全称 | NF-kappa-B inhibitor alpha |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 |
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